COMPARISON OF CLINICAL AND ANGIOGRAPHIC CHARACTERISTICS OF DIABETIC AND NON-DIABETIC PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

Authors

  • Bashir Ahmed National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan
  • Jehangir Ali Shah National Institute of Cardiovascular Diseases, Karachi, Pakistan
  • Rajesh Kumar National Institute of Cardiovascular Diseases, Karachi, Pakistan
  • Mahesh Kumar Batra National Institute of Cardiovascular Diseases, Karachi, Pakistan
  • Khalil Ahmed Shaikh National Institute of Cardiovascular Diseases, Karachi, Pakistan
  • Ali Ammar National Institute of Cardiovascular Diseases, Karachi, Pakistan
  • Ambreen Nisar National Institute of Cardiovascular Diseases, Karachi, Pakistan
  • Gulzar Ali National Institute of Cardiovascular Diseases, Karachi, Pakistan
  • Tahir Saghir National Institute of Cardiovascular Diseases, Karachi, Pakistan
  • Nadeem Qamar National Institute of Cardiovascular Diseases, Karachi, Pakistan

DOI:

https://doi.org/10.47144/phj.v55i4.2309

Abstract

Objectives: In this study, we evaluated the differences in clinical and angiographic profiles of ST-segment elevation myocardial infarction (STEMI) patients with and without diabetes mellitus (DM) at a tertiary care cardiac hospital in Karachi, Pakistan.

Methodology: This descriptive cross-sectional study was conducted at a tertiary care cardiac hospital in Karachi, Pakistan. The study included consecutive adult patients (≥ 18 years of age) diagnosed with STEMI undergoing primary percutaneous coronary intervention (PCI). Diabetic and non-diabetic patients were compared for clinical and angiographic profiles.

Results: The study sample consisted of 43.8% (218) diabetic patients. The mean age was 59.03 ± 9.69 years vs. 49.54 ± 11.53 years; p<0.001, proportion of females was 35.3% (77) vs. 14.6% (41); p<0.001, Killip class III or IV was (17) vs. 2.5% (7), and hypertension was 83% (181) vs. 56.8% (159); p<0.001 among the diabetic and non-diabetic group, respectively. The frequency of multi-vessel disease was 50.9% (111) vs. 39.6% (111), the significant left main disease was 5% (11) vs. 2.5% (7), and initial TIMI III flow was 19.3% (42) vs. 25.4% (71) in diabetic and non-diabetic patients, respectively.

Conclusion: In conclusion, diabetes in STEMI setting is associated with complex coronary artery diseases, more hemodynamic instability at presentation, and the presence of multiple co-morbid conditions.

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Published

2022-12-31

How to Cite

1.
Ahmed B, Shah JA, Kumar R, Batra MK, Shaikh KA, Ammar A, Nisar A, Ali G, Saghir T, Qamar N. COMPARISON OF CLINICAL AND ANGIOGRAPHIC CHARACTERISTICS OF DIABETIC AND NON-DIABETIC PATIENTS WITH ACUTE MYOCARDIAL INFARCTION. Pak Heart J [Internet]. 2022Dec.31 [cited 2024Nov.24];55(4):391-5. Available from: https://pakheartjournal1.pcs.org.pk/index.php/pk/article/view/2309

Issue

Vol. 55 No. 4 (2022): Pakistan Heart Journal

Section

Original Article

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Copyright (c) 2022 Pakistan Heart Journal

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