ASSOCIATION OF HYPERURICEMIA WITH CRITICAL CORONARY ARTERY DISEASE

Authors

  • Gul Zaman Khan Niazi CPEIC MULTAN
  • Jehan Zab CPEIC MULTAN
  • Fahar Adnan CPEIC, MULTAN
  • Nisar Ahmed CPEIC, MULTAN
  • Ammar Akhtar CPEIC Multan
  • Muhammad Sohail Saleemi CPEIC MULTAN

DOI:

https://doi.org/10.47144/phj.v53i2.1813

Abstract

Objective: The study was conducted to determine the association of increased serum Uric acid level (SUA) with critical coronary artery disease (CAD) in patients subjected to coronary angiography.

Methodology: 360 patients (180 cases with critical CAD and 180 controls without critical CAD) were enrolled in the study after taking informed consent. Demographic data like age, gender, diabetes mellitus, hypertension, family history of CAD, dyslipidemia, smoking and BMI was collected. Serum uric acid was advised and recorded in the questionnaire.

Results: 360 patients with mean age 51.37 ± 6.5 years were included. 262 patients (72.8%) were male. 54 patients (20.8%) had hyperuricemia.  26.6% cases and 15.0% controls had hyperuricemia. Hyperuricemia was significantly associated with critical CAD (OR=2.06, CI 1.22-3.49, p=0.007). The association persisted after stratification according to age, gender, diabetes, hypertension, dyslipidemia, smoking, family history of IHD and BMI.

Conclusion: There is a positive association between critical CAD and hyperuricemia.

Keywords: Coronary artery disease, Hyperuricemia, IHD

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Author Biographies

Gul Zaman Khan Niazi, CPEIC MULTAN

SENIOR REGISTRAR CARDIOLOGY

Jehan Zab, CPEIC MULTAN

SENIOR REGISTRAR CARDIOLOGY

Fahar Adnan, CPEIC, MULTAN

ASSISTANT PROFESSOR CARDIOLOGY

Nisar Ahmed, CPEIC, MULTAN

ASSOCIATE PROFESSOR CARDIOLOGY

Ammar Akhtar, CPEIC Multan

POST GRADUATE RESIDENT CARDIOLOGY

Muhammad Sohail Saleemi, CPEIC MULTAN

ASSISTANT PROFESSOR CARDIOLOGY

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Published

2020-07-17

How to Cite

1.
Niazi GZK, Zab J, Adnan F, Ahmed N, Akhtar A, Saleemi MS. ASSOCIATION OF HYPERURICEMIA WITH CRITICAL CORONARY ARTERY DISEASE. Pak Heart J [Internet]. 2020Jul.17 [cited 2024Nov.24];53(2). Available from: https://pakheartjournal1.pcs.org.pk/index.php/pk/article/view/1813

Issue

Vol. 53 No. 2 (2020): Pakistan Heart Journal

Section

Original Article

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