SEVERITY OF CORONARY ARTERY DISEASE IN NON-ST ELEVATION MYOCARDIAL INFARCTION (NSTEMI) PATIENTS WITH HIGH TROPONIN-I LEVEL

Authors

  • Sajid Ali Shaikh
  • Ghulam Abbas Shaikh
  • Musa Karim

DOI:

https://doi.org/10.47144/phj.v51i2.1490

Abstract

Objective: To determine the frequency of severity of obstructive coronary arterydisease or left main coronary artery stenosis in NSTEMI patients with elevatedTroponin-I level.

Methodology: This cross-sectional study was conducted at National Institute ofCardiovascular Diseases (NICVD), Karachi from 25 January to 24 July 2015.Weincluded patients diagnosed with NSTEMI, between 40-72 years of age. Patientswere classified as low risk (Group A) and high risk (Group B) based on criteria ofelevated troponin I level more than tenfold the maximum threshold of the normalrange. Chi square test or Fisher's Exact test, Kruskal-Wallis Test, and independentsample t-test were applied as appropriate and two sided p 0.05 was used as acriterion for statistical significance.

Results: Total 123 Patients were included. There were 95 (77.24%) malepatients. Mean age was 54.72±8.27 years. Of total 25(20.33%) of the patientswere in high risk group. Normal angiogram was observed in a significantly highnumber of lower risk group (Group A) as compared to higher risk group (GroupB), 13(13.27%) vs. 0(0%). SVD was observed in 35(35.71%) vs. 1(4%) ofpatients of lower risk group and higher risk group. (p = 0.001), 2VD wasobserved in 26(26.53%) vs. 12(48%) (p= 0.036) and 3VD was observed in24(24.49%) vs. 12(48%) (p=0.022).

Conclusion: Elevated troponin I levels, more than tenfold of the maximumthreshold of the normal range, in non-ST elevated myocardial infarction(NSTEMI) patients are strongly associated with more complex and severecoronary artery disease.

Key Words: Myocardial Infarction, NSTEMI, Angiography, Acute CoronarySyndrome, Troponin.

 

 

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How to Cite

1.
Shaikh SA, Shaikh GA, Karim M. SEVERITY OF CORONARY ARTERY DISEASE IN NON-ST ELEVATION MYOCARDIAL INFARCTION (NSTEMI) PATIENTS WITH HIGH TROPONIN-I LEVEL. Pak Heart J [Internet]. 2018Oct.22 [cited 2024Nov.24];51(2). Available from: https://pakheartjournal1.pcs.org.pk/index.php/pk/article/view/1490

Issue

Vol. 51 No. 2 (2018): Pakistan Heart Journal

Section

Original Article

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