ROLE OF HERBAL FORMULATION OF GARLIC ON LIPID PROFILE IN PATIENTS WITH TYPE 2 DIABETES RELATED DYSLIPIDEMIA

Authors

  • Naveed Ali Siddiqui
  • Saida Haider
  • Mohammad Misbah-ur- Rehman
  • Tahira Perveen

DOI:

https://doi.org/10.47144/phj.v49i4.1159

Abstract

Objective: To evaluate the role and side effects of garlic on lipid profile in diabeticdyslipidemic patients along with their lipid lowering efficacy.

Methodology: This cross sectional study was carried out at Surgeon MunawarMemorial Hospital Bahadurabad Karachi. The study period consisted of 8 weeksst st from 1 February 2015 to 31 March 2015. Patients with age between 30 and 60years of either gender with diabetic dyslipidemia were included . The exclusioncriteria included pregnant/lactating females, liver, renal and establishedcoronary artery disease or ischemic heart disease.

Results: Total of 30 diabetic dyslipidemic patients with abnormal lipid profilewere included. Patients were orally administered with local herbal product ofgarlic (300 mg/day) for 8 weeks. Serum levels of cholesterol, high densitylipoprotein (HDL), triglyceride (TG), and low density lipoprotein (LDL) wereestimated in patients before and after treatment with local herbal product of garlic(300 mg/day). After the treatment of garlic, serum cholesterol and low densitylipoprotein were significantly decreased but there was no effect on triglyceridelevels (p >0.05).

Conclusion: On the basis of this study we concluded that herbal products likegarlic significantly decreases cholesterol, low density lipoprotein (LDL) andincreases high density lipoprotein (HDL).

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How to Cite

1.
Siddiqui NA, Haider S, Rehman MM- ur-, Perveen T. ROLE OF HERBAL FORMULATION OF GARLIC ON LIPID PROFILE IN PATIENTS WITH TYPE 2 DIABETES RELATED DYSLIPIDEMIA. Pak Heart J [Internet]. 2017Feb.23 [cited 2024Nov.24];49(4). Available from: https://pakheartjournal1.pcs.org.pk/index.php/pk/article/view/1159

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Original Article